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Creating the next generation of highly detailed human brain models by building on the BigBrain - the first openly accessible, microscopic resolution 3D model of the human brain.

News About the BigBrain

Featured: Siibra
date: Dec 01 2021
Our featured project the siibra toolsuite.
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Mapping the brain
date: Oct 13 2021
Scientists at Forschungszentrum Jülich are working on three-dimensional maps of the human brain. This is their contribution to the large-scale European Human Brain Project (HBP).
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MAIN 2021
date: Nov 29-30th
Montreal AI & Neuroscience (MAIN) 2021 Conference, Nov 29-30th
Participation is free but registration is mandatory (register here)
Contributions are welcome (Submit an Abstract)
Educational sessions: Nov 25-26th
For event details, click here
5th BigBrain Workshop
date: Oct 04 2021
Recordings are now available for the BigBrain Workshop 2021. Please visit our YouTube channel.
For event details, click here
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Eric Upschulte Mitacs Award
date: Sept 27 2021
Eric Upschulte (INM-1, FZJ) joins Alan Evan's lab for a three month research stay, for which he received a Mitacs Globalink Research Award To Canada in 2020.
Alan Evans awarded 2021 RSC McLaughlin Medal
date: Sept 17 2021
Congratulations! Alan Evans is the 2021 RSC McLaughlin Medal awardee for excellence and achievement in medical science for his significant contributions to the field of neuroimaging.
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Christian Schiffer Mitacs Award
date: Sept 15 2021
Christian Schiffer (INM-1, FZJ) received a Mitacs Globalink Research Award To Canada - Healthy Brains for Healthy Lives (HBHL) and will join Alan Evan's lab for a three month research stay next year.
Convolutional Neural Networks for cytoarchitectonic brain mapping at large scale
date: Sept 2021
A novel method for automatic classification of cytoarchitectonic brain areas in large series of consecutive histological brain sections.
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About the BigBrain

Full dataset over 1TB

Scans at 20μm resolution

Multiple formats

An expanding brain atlas

A thriving community

What People Say About the BigBrain

Why create the BigBrain

A message from Dr. Zilles

the major advantage of the BigBrain for our work is that the image data of the human brain are registered as a 3D volume at very high spatial resolution. Since the human brain is folded, any part of the cortical ribbon may be subjected to the geometrical effects of this folding, i.e. the cortex is obliquely or even tangentially sectioned at various sites in a 2D representation, e.g. in images of single microtome sections. This effect hampers the measurement of any cortical structure which is bound to the 3D columnar architecture of the cortex. In contrast, the BigBrain allows analyses in 3D, and thus has opened the door to many studies which would not be possible in 2D representations.

Martha Crago

Vice-Principal (Research + Innovation) McGill University

With HIBALL the partnership between two world-leading research institutions in computational neuroscience will provide an important platform for the scientists to conduct innovative, interdisciplinary, and complementary research in a rich and collaborative setting.

Yoshua Bengio

Mila Scientific Director, Quebec Artificial Intelligence Institute

HIBALL assembles a team with world-leading expertise in neuroimaging, artificial intelligence, neuroscience and neuroinformatics, which complements well the team at Mila. The active participation of several PIs with ties to Mila is very exciting, and we anticipate this lab will further expand the collaboration between neuroscience and AI experts in the Montreal ecosystem, leading to cutting-edge discoveries in both fields.

Viktor Jirsa

Directeur de Recherche, CNRS

HIBALL can build on a remarkable expertise and international reputation and will lead to high impact contributions in Human Brain Atlasing, Neuroinformatics, and Machine Learning.